The dosage of oxcarbazepine needs reducing in people with kidney disease.Although dosages greater than 1200 mg/day in adults have shown greater efficacy, most people cannot tolerate the CNS side effects that occur with these dosages.Oxcarbazepine can inhibit some liver enzymes (notably CYP2C19 and CYP3A4/5), which may affect plasma levels of some other medications, including oral contraceptives and felodipine.Anaphylaxis (serious allergic reactions) is rare. Nausea, vomiting, double vision, headache, and nystagmus (rapid side-to-side eye movements) are also common.Central nervous system (CNS) side effects, including a slowing in the speed of information processing, difficulty with concentration, dizziness, speech and language problems, sleepiness and fatigue, and coordination difficulties including muscle movement disorders and gait disturbances.If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Cost-saving, generic oxcarbazepine is available.Brand names of oxcarbazepine include Trileptal and Oxtellar.Oxcarbazepine is available in tablet form or as a suspension.The abuse potential of oxcarbazepine is unknown. Oxcarbazepine does not appear to cause dependence or tolerance, although a slow withdrawal is recommended to avoid precipitating seizures.It may be used off-label (not an FDA-approved use) to treat other conditions such as bipolar disorder or migraine.May be used as the sole therapy for the treatment and prevention of partial seizures in children over the age of four, or in addition to other medications for epilepsy in children over the age of two.May be used for the treatment and prevention of partial seizures in adults, either alone or in addition to other anti-seizure medicines.Oxcarbazepine belongs to the class of medicines known as dibenzazepine carboxamides.The exact way oxcarbazepine and its active metabolite exert their antiseizure activity is not known however, it is thought to be by stabilizing nerve membranes, which reduces repetitive firing. Once in the body, it is metabolized in the liver to another compound, called MHD, which also helps to reduce seizure frequency.Oxcarbazepine is an anticonvulsant that reduces the frequency of certain types of seizures.Medically reviewed by Carmen Fookes, BPharm.